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The process of mineralisation in the development of human tooth

Type:  Articles

Pubblication date:  /1/2016

Authors:  S. Caruso*, S. Bernardi*, M. Pasini**, M.R. Giuca**, R. Docimo***, M.A. Continenza*, R. Gatto*

Language:  English

Institution:  *Department of Health, Life and Environmental Sciences, University of L’Aquila. **Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa ***Department of Experimental Medicine and Surgery, University of Rome “Tor Vergata”

Publication:  European Journal of Paediatic Dentistry

Publisher:  Ariesdue Srl

Keywords:  Enamel disorders; Germ and tooth development; Tooth mineralisation.

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Email:  [email protected]

Title:  The process of mineralisation in the development of human tooth

Abstract:  Aim Tooth development and mineralisation are processes that derive from different tissues interactions, in particular ectodermal and mesenchymal layers. These interactions are responsible for the formation of unique structures with a particular chemical composition. Despite differences, mineralised tissues are similar and they derive by highly concerted extracellular processes that involve matrix proteins, proteases, and mineral ion fluxes that collectively regulate the nucleation, growth and organisation of forming mineral crystals. This review aims at explaining mineralisation, its stages and when damage occurs and alters the hard tissues structure.

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