Very large Ameloblastic Fibroma with Calcifying Odontogenic Cyst in an 8-year-old child. Histological and immunohistochemical characterisation

Authors:

  • T. Cutilli
    Department of Life, Health and Environmental Sciences, University of L’Aquila, Maxillofacial Surgery Operative Unit, San Salvatore City Hospital, L’Aquila, Italy
  • G. Coletti
    Department of Life, Health and Environmental Sciences, University of L’Aquila, Pathology Operative Unit, San Salvatore City Hospital, L’Aquila, Italy
  • M. W. Fatayer
    Department of Life, Health and Environmental Sciences, University of L’Aquila, Pathology Operative Unit, San Salvatore City Hospital, L’Aquila, Italy
  • S. Caruso
    Dental School, Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy
  • S. Tecco
    Dental School, Vita-Salute San Raffaele University, Milan, Italy
  • R. Gatto
    Dental School, Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy
  • P. Leocata
    Department of Life, Health and Environmental Sciences, University of L’Aquila, Pathology Operative Unit, San Salvatore City Hospital, L’Aquila, Italy

DOI:

https://doi.org/10.23804/ejpd.2019.20.01.04

ABSTRACT


Aim

Ameloblastic fibroma (AF) is an uncommon odontogenic tumour that may present an aggressive behaviour and may have potential for malignant transformation. Ghost cell (GC) differentiation within AF is extremely rare. There are only seven cases in the international literature in which ghost cells are found in AF.

Case report

In this study, we report a case of a 8-year-old female child with a cystic-solid mass, measuring 3 x 1.7 x 1.2 cm, characterised by mixed odontogenic tumour, with AF in most of the lesion, with areas characterised by GC, while ameloblastic and ameloblastic fibrodontoma areas were also detected. Other histological sections showed only AF tissue, with areas of Calcifying Odontogenic Cyst. The immunohistochemical characterisation of the lesion was also performed. A comparative table of the immunoistochemical staining of the AF and COC areas revealed some differences in the expression of markers.

PLUMX METRICS

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Publication date:

March /2019

Issue:

Vol.20 – n.1/2019

Page:

19 – 22

Publisher:

Ariesdue

Cite:


Harvard: T. Cutilli, G. Coletti, M. W. Fatayer, S. Caruso, S. Tecco, R. Gatto, P. Leocata (2019) "Very large Ameloblastic Fibroma with Calcifying Odontogenic Cyst in an 8-year-old child. Histological and immunohistochemical characterisation", European Journal of Paediatric Dentistry, 20(1), pp19-22. doi: 10.23804/ejpd.2019.20.01.04
Vancouver: T. Cutilli, G. Coletti, M. W. Fatayer, S. Caruso, S. Tecco, R. Gatto, P. Leocata. Very large Ameloblastic Fibroma with Calcifying Odontogenic Cyst in an 8-year-old child. Histological and immunohistochemical characterisation. European Journal of Paediatric Dentistry [Internet]. 2019Mar.1 [cited 2022Jul.07];20(1):19-22. Available from: https://www.ejpd.eu/abstract-pubmed/very-large-ameloblastic-fibroma-with-calcifying-odontogenic-cyst-in-an-8-year-old-child-histological-and-immunohistochemical-characterisation/
MLA: T. Cutilli, G. Coletti, M. W. Fatayer, S. Caruso, S. Tecco, R. Gatto, P. Leocata Very large Ameloblastic Fibroma with Calcifying Odontogenic Cyst in an 8-year-old child. Histological and immunohistochemical characterisation. European Journal of Paediatric Dentistry. 2019;20(1):19-22

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