Salivary microbiota and caries occurrence in Mutans Streptococci-positive school children

Authors:

  • M. ElSalhy
    Faculty of Dentistry, Kuwait University, Kuwait - Institute of Dentistry, University of Turku, Finland
  • E. Sderling
    Institute of Dentistry, University of Turku, Finland
  • E. Honkala
    Faculty of Dentistry, Kuwait University, Kuwait
  • M. Fontana
    Department of Cariology, Restorative Sciences Endodontics, School of Dentistry, University of Michigan, Ann Arbor, USA
  • S. Flannagan
    Department of Cariology, Restorative Sciences Endodontics, School of Dentistry, University of Michigan, Ann Arbor, USA
  • A. Kokaras
    Department of Microbiology, The Forsyth Institute, Cambridge, USA
  • B. J. Paster
    Department of Oral Medicine, Infection AND Immunity, Harvard School of Dental Medicine, Boston, USA
  • A. Varghese
    Faculty of Dentistry, Kuwait University, Kuwait
  • S. Honkala
    Faculty of Dentistry, Kuwait University, Kuwait

ABSTRACT


Aim

To compare the composition of the salivary microbiota in caries-affected vs. caries-free mutans streptococci (MS)-
positive children with mixed dentition.

Methods

Twenty eight healthy, 11-12-year-old schoolchildren with high MS
counts (>105 CFU/mL) were included in this study. The children were screened with the Dentocult SM Strip Mutans test (Orion
Diagnostica, Espoo, Finland) and examined using the International Caries Detection and Assessment System (ICDAS). The microbial
composition of the saliva was assessed using the Human Oral Microbe Identification Microarray (HOMIM). Microbial differences
between caries-affected (n18) and caries-free children (n10) were compared by Mann-Whitney analysis.

Results

The microbiota of the caries-affected vs. caries-free children was rather similar. Abiotrophia defectiva and Actinomyces meyeri/A.
odontolyticus were significantly higher in caries-affected than in caries-free children (p0.006, 0.046, respectively).
Shuttleworthia satelles was significantly higher in caries-free compared to caries-affected children (p0.031). A. defectiva and A.
meyeri/A. odontolyticus correlated positively with caries severity measured by ICDAS Caries Index (p 0.494, 0.454, 0.400
respectively) while S. satelles was negatively correlated with caries severity (p -0.489). CONCLUSIONS: Salivary A. defectiva
and A. meyeri/A. odontolyticus and are associated with caries occurrence in MS-positive children with mixed dentition.

PLUMX METRICS

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Publication date:

Sep /2016

Keywords:

caries prevalence, children with mixed dentition, salivary microbiota

Issue:

Vol.17 – n.3/2016

Page:

188 – 192

Publisher:

Ariesdue

Cite:


Harvard: M. ElSalhy, E. Sderling, E. Honkala, M. Fontana, S. Flannagan, A. Kokaras, B. J. Paster, A. Varghese, S. Honkala (2016) "Salivary microbiota and caries occurrence in Mutans Streptococci-positive school children", European Journal of Paediatric Dentistry, 17(3), pp188-192. doi: https://www.ejpd.eu/wp-content/uploads/pdf/EJPD_2016_3_3.pdf
Vancouver: M. ElSalhy, E. Sderling, E. Honkala, M. Fontana, S. Flannagan, A. Kokaras, B. J. Paster, A. Varghese, S. Honkala. Salivary microbiota and caries occurrence in Mutans Streptococci-positive school children. European Journal of Paediatric Dentistry [Internet]. 2016Sep.1 [cited 2025May.23];17(3):188-192. Available from: https://www.ejpd.eu/abstract-pubmed/salivary-microbiota-and-caries-occurrence-in-mutans-streptococci-positive-school-children/
MLA: M. ElSalhy, E. Sderling, E. Honkala, M. Fontana, S. Flannagan, A. Kokaras, B. J. Paster, A. Varghese, S. Honkala Salivary microbiota and caries occurrence in Mutans Streptococci-positive school children. European Journal of Paediatric Dentistry. 2016;17(3):188-192

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