• About
  • Editorial Board
  • Current Issue
  • Early access
  • Archive
Search
EJPD
  • About
  • Editorial Board
  • Current Issue
  • Early access
  • Archive
  • Sioi
  • Guidelines for Authors
  • Article submission
  • Terms of use
  • Privacy
Home Revascularisation versus apexification for treatment of immature teeth based on periapical healing...

Revascularisation versus apexification for treatment of immature teeth based on periapical healing and root development: A systematic review and meta-analysis

Authors:

  • Y. Xie
    The Department of Stomatology, Jieyang Affiliated Hospital, SunYat-sen University, Jieyang, Guangdong, PR China
  • F. Lu
    The Intensive Care Unit, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, PR China
  • Y. Hong
    The Intensive Care Unit, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, PR China
  • J. He
    The Clinical Medicine Research Laboratory, Jieyang Affiliated Hospital, SunYat-sen University, Jieyang, Guangdong, PR China
  • Y. Lin
    The Department of Stomatology, Jieyang Affiliated Hospital, SunYat-sen University, Jieyang, Guangdong, PR China

DOI:

https://doi.org/10.23804/ejpd.2021.22.03.6

ABSTRACT


Aim

Immature necrotic teeth are frequent findings in adolescents that may lead to thin root walls and open apexes. The absence of an apical stop becomes a challenge for endodontic treatment because it is difficult or impossible to seal the immature root canal with conventional endodontic techniques. Revascularisation therapy (RET) may be more suitable for the treatment of immature necrotic teeth. However, clinicians are still more inclined to choose apexification (AP) when considering the predictability of treatment results.

Methods

The literature was searched via PubMed/MEDLINE and the Cochrane Library, Web of Science data from June, 2001 to September, 2020 and randomised clinical trials were selected that compared RET with AP for the treatment of immature necrotic teeth assessing clinical and radiographic results.

Results

A total of 556 articles were retrieved, though only five studies were included. There were no differences in the periapical healing rate, overall effective rate/invalid rate, or apical closure rate between RET and AP. The root length was significantly increased in the RET group compared with the AP group quantitatively (pooled difference in means=1.28, 95% CI: [1.08, 1.48], Z=12.69, P<0.00001) and qualitatively (pooled RR=4.12, 95% CI: [2.44, 6.97]), Z=5.28, P<0.00001). The effective rate of root thickness was significantly increased in the RET group compared with the AP group (pooled RR=22.63, 95% CI: [6.08, 84.26]), Z=4.65, P<0.00001).

Conclusion

Both RET and AP were effective options regarding the healing of periapical periodontitis or the closure of open apices. Pulp revascularisation is more effective for root elongation and thickening without higher risk of overall invalid treatment.

PLUMX METRICS

Download PDF

Publication date:

September /2021

Issue:

Vol.22 – n.3/2021

Page:

207 – 214

Publisher:

Ariesdue

Topic:

Pulp therapy for primary & young permanent teeth

Cite:


Harvard: Y. Xie, F. Lu, Y. Hong, J. He, Y. Lin (2021) "Revascularisation versus apexification for treatment of immature teeth based on periapical healing and root development: A systematic review and meta-analysis", European Journal of Paediatric Dentistry, 22(3), pp207-214. doi: 10.23804/ejpd.2021.22.03.6
Vancouver: Y. Xie, F. Lu, Y. Hong, J. He, Y. Lin. Revascularisation versus apexification for treatment of immature teeth based on periapical healing and root development: A systematic review and meta-analysis. European Journal of Paediatric Dentistry [Internet]. 2021Sep.1 [cited 2023Mar.25];22(3):207-214. Available from: https://www.ejpd.eu/abstract-pubmed/revascularisation-versus-apexification-for-treatment-of-immature-teeth-based-on-periapical-healing-and-root-development-a-systematic-review-and-meta-analysis/
MLA: Y. Xie, F. Lu, Y. Hong, J. He, Y. Lin Revascularisation versus apexification for treatment of immature teeth based on periapical healing and root development: A systematic review and meta-analysis. European Journal of Paediatric Dentistry. 2021;22(3):207-214

Copyright (c) 2021 Ariesdue

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Facebook
Twitter
Pinterest
Linkedin
WhatsApp
Email
Print
    webfactory.bm24
    Editor in chief: dott. Luigi Paglia
    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
    powered by Ariesdue

    CONTACT US
    • About
    • Editorial Board
    • Current Issue
    • Early access
    • Archive
    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
    Registrazione del Tribunale di Milano n. 285 del 14.04.1998 | ROC 1946 - 26.09.2001
    /* ----------------------------------------- */ /* Modello di contenuto: Abstracts PubMed - inizio */ /* ----------------------------------------- */ /* ----------------------------------------- */ /* Modello di contenuto: Abstracts PubMed - fine */ /* ----------------------------------------- */