The purpose of this article is to report some unusual characteristics related to gender, location and
manifestations of severe Regional Odontodysplasia detected in three subjects. Regional Odontodysplasia is a rare
disturbance of dental development whose aetiology is still unknown. Anomalies involve enamel, dentin, pulp and dental
follicle causing atypical structure, colour, shape, size and eruptive disturbances of the affected teeth. Its early onset may lead
to craniofacial development disturbances. CASES REPORTS: This article reports three cases with unusual characteristics
observed in male children who were assisted by a paediatric dentist. Generally the disease affects one hemiarch and it is
very rare that it crosses the midline as in one of the presented cases. Regional Odontodysplasia has been predominantly
described in the maxilla and in women, however these three cases are in boys and two of them occured in the mandible.
Regional Odontodysplasia is a rare disease, causing severe dental, growing and craniofacial development
anomalies. Treatment needs to be personalised, aiming at preservation of the affected teeth taking into account their risk to
develop severe infections. Parents should be made aware of the need for an extensive follow-up.
Vol.13 – n.2/2012
Harvard: E. Barbera, A. Sanz Coarasa, A. Hernndez, C. Cardoso-Silva (2012) "Regional Odontodysplasia. A literature review and three case reports", European Journal of Paediatric Dentistry, 13(2), pp161-166. doi:
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