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Home Regeneration of new periodontal attachment following surgical removal of a Peripheral Giant...

Regeneration of new periodontal attachment following surgical removal of a Peripheral Giant Cell Granuloma in a young patient: an 8-year follow-up

Authors:

  • A. Cuozzo
    Department Of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Italy
  • L. Mauriello
    Department Of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Italy
  • V. Iorio-Siciliano
    Department Of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Italy
  • A. Blasi
    Department Of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Italy
  • F. Riccitiello
    Department Of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Italy
  • L. Ramaglia
    Department Of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Italy

DOI:

https://doi.org/10.23804/ejpd.2025.2237

ABSTRACT


Background

Peripheral Giant Cell Granuloma (PGCG) is a rare benign lesion of the oral cavity originating from periosteum and gingival connective tissue, associated to local irritant and/or traumatic factors. Clinically PGCG appears as a painless swelling lesion with a smooth surface, brown red or purple in colour, ranging from few millimeters to 3-4 centimeters. The aim of this case report is to demonstrate the complete periodontal and bone regeneration after elimination of traumatic factors and surgical therapy.

Case report

A 12-year-old female patient complained a gingival swelling in region 2.1, following an orthodontic therapy. Following a careful evaluation of data collected by anamnesis and clinical and radiograph exams, the surgical excision of the lesion was scheduled. PGCG was confirmed by histological analysis. Finally, a series of follow up at one-, two-, three-, and eight-year were scheduled.

Conclusion

The long-term follow-ups seem to demonstrate that the surgical removal of a PGCG associated with bone resorption and deep periodontal pockets caused by development of the lesion may lead to the regeneration of new periodontal attachment for both the infrabony and the suprabony component of the periodontal pocket.

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Publication date:

September /2025

Issue:

Vol.26 – n.3/2025

Page:

208 – 211

Publisher:

Tecniche Nuove

Topic:

Paediatric oral pathology

Cite:


Harvard: A. Cuozzo, L. Mauriello, V. Iorio-Siciliano, A. Blasi, F. Riccitiello, L. Ramaglia (2025) "Regeneration of new periodontal attachment following surgical removal of a Peripheral Giant Cell Granuloma in a young patient: an 8-year follow-up", European Journal of Paediatric Dentistry, 26(3), pp208-211. doi: 10.23804/ejpd.2025.2237
Vancouver: A. Cuozzo, L. Mauriello, V. Iorio-Siciliano, A. Blasi, F. Riccitiello, L. Ramaglia. Regeneration of new periodontal attachment following surgical removal of a Peripheral Giant Cell Granuloma in a young patient: an 8-year follow-up. European Journal of Paediatric Dentistry [Internet]. 2025Sep.1 [cited 2025Dec.05];26(3):208-211. Available from: https://www.ejpd.eu/abstract-pubmed/regeneration-of-new-periodontal-attachment-following-surgical-removal-of-a-peripheral-giant-cell-granuloma-in-a-young-patient-an-8-year-follow-up/
MLA: A. Cuozzo, L. Mauriello, V. Iorio-Siciliano, A. Blasi, F. Riccitiello, L. Ramaglia Regeneration of new periodontal attachment following surgical removal of a Peripheral Giant Cell Granuloma in a young patient: an 8-year follow-up. European Journal of Paediatric Dentistry. 2025;26(3):208-211

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    Editor in chief: dott. Luigi Paglia
    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
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    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
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