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Home Nickel, chromium and methyl methacrylate monomer release from orthopaedic functional appliances

Nickel, chromium and methyl methacrylate monomer release from orthopaedic functional appliances

Authors:

  • E-J Ahn
    Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea Department of Orthodontics, Kyung Hee University Dental Hospital at Gangdong, Seoul, Korea
  • S-J Kim
    Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea Department of Orthodontics, Kyung Hee University Dental Hospital at Gangdong, Seoul, Korea
  • S-H Kim
    Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea Department of Orthodontics, Kyung Hee University Dental Hospital at Gangdong, Seoul, Korea
  • K-H Park
    Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea Department of Orthodontics, Kyung Hee University Dental Hospital at Gangdong, Seoul, Korea
  • W-W Jang
    Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea Department of Orthodontics, Kyung Hee University Dental Hospital at Gangdong, Seoul, Korea
  • Y-G Kang
    Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea Department of Orthodontics, Kyung Hee University Dental Hospital at Gangdong, Seoul, Korea

DOI:

https://doi.org/10.23804/ejpd.2021.22.02.11

ABSTRACT


Aim

This study was purposed to evaluate release of nickel and chromium ions and methyl methacrylate (MMA) monomers from functional appliances and their possible health effects.

Material and methods

Study design: Twin-block appliances and Bionators were immersed in artificial saliva and kept in a thermal incubator. Control group was established as artificial saliva without appliances. Artificial saliva was analysed after 7 days, 30 days and 90 days. Inductively coupled plasma mass spectrometry and gas chromatography–mass spectrometry was used for detection of nickel and chromium ions and MMA monomers. MTT assays and cytokine array were performed. Statistics: One way ANOVA with Tukey test and Dunnett’s T3 for post-hoc analysis was used for evaluation of time-dependent changes and independent t-test was used for evaluation of MTT assay results.

Results

The results revealed that metal ions and MMA monomers are released from the appliances. Metal ion detection pattern was irregular and could not be analysed. Twin-block group showed significantly larger amount of MMA release. MTT assay revealed statistically significant but minimally reduced cellular activity on Bionator and twin-block groups compared to control groups. Cytokine array showed no or less inflammatory cytokine release on Bionator and twin-block groups.

Conclusion

MMA monomer release was confirmed but the cytotoxic effect of functional appliance material release is minimal or negligible. General toxicity of the functional appliance from the MMA monomer release is likely to be minimal or negligible.

PLUMX METRICS

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Publication date:

June /2021

Issue:

Vol.22 – n.2/2021

Page:

144 – 150

Publisher:

Ariesdue

Topic:

Developing dentition and occlusion in paediatric dentistry

Cite:


Harvard: E-J Ahn, S-J Kim, S-H Kim, K-H Park, W-W Jang, Y-G Kang (2021) "Nickel, chromium and methyl methacrylate monomer release from orthopaedic functional appliances", European Journal of Paediatric Dentistry, 22(2), pp144-150. doi: 10.23804/ejpd.2021.22.02.11
Vancouver: E-J Ahn, S-J Kim, S-H Kim, K-H Park, W-W Jang, Y-G Kang. Nickel, chromium and methyl methacrylate monomer release from orthopaedic functional appliances. European Journal of Paediatric Dentistry [Internet]. 2021Jun.1 [cited 2023Sep.27];22(2):144-150. Available from: https://www.ejpd.eu/abstract-pubmed/nickel-chromium-and-methyl-methacrylate-monomer-release-from-orthopaedic-functional-appliances/
MLA: E-J Ahn, S-J Kim, S-H Kim, K-H Park, W-W Jang, Y-G Kang Nickel, chromium and methyl methacrylate monomer release from orthopaedic functional appliances. European Journal of Paediatric Dentistry. 2021;22(2):144-150

Copyright (c) 2021 Ariesdue

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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    Editor in chief: dott. Luigi Paglia
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    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
    Registrazione del Tribunale di Milano n. 285 del 14.04.1998 | ROC 1946 - 26.09.2001
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