Evaluation of two different remineralising toothpastes in children with drug-controlled asthma and allergic rhinitis: a randomised clinical trial

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ABSTRACT

Aim

To compare the efficacy of two remineralising toothpastes in children suffering from asthma and allergic rhinitis after a 6-month study.

Methods

40 patients aged between 6-14 years with enamel demineralisations were enrolled for the study at the Unit of Dental Hygiene of the University of Pavia (Italy). The following indices were collected: Schiff air index (SAI), plaque index (PI), bleeding on probing (BoP), salivary pH, Basic Erosive Wear Examination (BEWE), susceptibility index (SI) for hard and soft tissues’ pathologies, and decayed missing filled teeth (DMFT). After mechanical debridement with piezoelectric instrumentation and glycine powder, patients were equally divided into two groups: Group 1 using a toothpaste with zinc hydroxyapatite, and Group 2 using a toothpaste containing calcium sodium phosphosilicate. The toothpaste had to be used twice a day. The time frames of the study were: baseline (T0), after 1 month (T1), after 3 months (T2), after 6 months (T3).

Results

PI, BoP, SAI were significantly reduced in both the Groups after the 6-month treatment (p<0.05), with no significant intergroup differences (p>0.05). SI resulted to be significantly reduced in Group 1 from T2 to T3 (p<0.05), while the same did not happen for Group 2 (p>0.05) and no intergroup differences were found (p>0.05). Salivary pH, DMFT and BEWE did not exhibit inter- and intragroup significant differences (p>0.05).

Conclusion

The tested toothpastes can be proposed for home use in children with asthma and allergic rhinitis as they significantly reduced dental sensitivity and periodontal indices.

Study Design

Single-center, parallel, active-controlled randomised clinical trial with 1:1 allocation ratio. Trial registration: NCT05631197.

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