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Home Effects of maltitol and xylitol chewing-gums on parameters involved in dental caries...

Effects of maltitol and xylitol chewing-gums on parameters involved in dental caries development

Authors:

  • C. Thabuis
    Roquette, France
  • C. Y. Cheng
    Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, Beijing, China
  • X. Wang
    Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, Beijing, China
  • M. Pochat
    Roquette, France
  • A. Han
    Roquette, Shanghai, China
  • L. Miller
    Sprim USA, San Francisco, USA
  • D. Wils
    Roquette, France
  • L. Guerin-Deremaux
    Roquette, France

ABSTRACT


Aim

The effects on plaque parameters of sugar free chewing-gums (CG) sweetened with either maltitol or xylitol were
assessed to better understand the role polyols can play in dental caries prevention.

Methods

A double-blind,
parallel, randomised, controlled study was conducted in China. Subjects (N = 258, age = 13 to 15 years-old) were divided into 4 groups:
2 receiving polyols CG, containing respectively maltitol or xylitol, a group receiving gum base (placebo) and a negative control group not
receiving any gum. CG were chewed for 30 days. This corresponds to a 10 g consumption of polyol per day. Plaque parameters
(growth, pH, bacteria and insoluble glucans) were evaluated throughout the experimental period.

Results

All parameters studied
were significantly modified with gum base compared to no-gum: plaque pH increased; plaque growth, bacteria (S. mutans, S. sobrinus,
A. viscosus and Lactobacillus) and insoluble glucans decreased. Maltitol and xylitol CG led similarly to a higher plaque pH (AUC,
p0.05) on short (at baseline after the first CG consumption) and long term (after 4 weeks of daily CG consumption), with or without
saliva stimulation compared to both control and placebo groups. They led to a decrease in plaque growth (p=0.02) over the
experimental period compared to controls. Moreover, they significantly reduced the concentration of 4 cariogenic bacteria species
(p0.05) in dental plaque compared to gum base.

Conclusion

Sugar free CG sweetened with either maltitol or xylitol can
similarly reduce plaque acidogenicity compared to gum base through a decrease in oral bacteria presence. The use of a gum base
placebo allowed to isolate effects on parameters involved in dental caries development specific to maltitol and xylitol, and to show these
effects were similar.

PLUMX METRICS

Publication date:

Dec /2013

Keywords:

dental caries, maltitol, polyol, xylitol

Issue:

Vol.14 – n.4/2013

Page:

303 – 308

Publisher:

Ariesdue

Cite:


Harvard: C. Thabuis, C. Y. Cheng, X. Wang, M. Pochat, A. Han, L. Miller, D. Wils, L. Guerin-Deremaux (2013) "Effects of maltitol and xylitol chewing-gums on parameters involved in dental caries development", European Journal of Paediatric Dentistry, 14(4), pp303-308. doi:
Vancouver: C. Thabuis, C. Y. Cheng, X. Wang, M. Pochat, A. Han, L. Miller, D. Wils, L. Guerin-Deremaux. Effects of maltitol and xylitol chewing-gums on parameters involved in dental caries development. European Journal of Paediatric Dentistry [Internet]. 2013Dec.1 [cited 2025May.16];14(4):303-308. Available from: https://www.ejpd.eu/abstract-pubmed/effects-of-maltitol-and-xylitol-chewing-gums-on-parameters-involved-in-dental-caries-development/
MLA: C. Thabuis, C. Y. Cheng, X. Wang, M. Pochat, A. Han, L. Miller, D. Wils, L. Guerin-Deremaux Effects of maltitol and xylitol chewing-gums on parameters involved in dental caries development. European Journal of Paediatric Dentistry. 2013;14(4):303-308

Copyright (c) 2021 Ariesdue

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
    Registrazione del Tribunale di Milano n. 285 del 14.04.1998 | ROC 1946 - 26.09.2001
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