Sedation regimens for toddlers and preschoolers are still open for further studies. Propofol is rapidly finding its way into
medical routine. The aim of this pilot study was to re-evaluate the need for sedation in young children and to further investigate the use
of propofol as an intravenous agent combined with the use of a flexible laryngeal mask for treatment of the youngest group of dental
A randomised clinical trial with 54 children involved was conducted comparing one group receiving propofol
sedation only with a study group receiving propofol with the use of a reinforced laryngeal mask. Assessments were made as to depth of
sedation, quantity of propofol used, desaturations and recovery times.
The use of a laryngeal mask improved the treatment
conditions by decreasing the number of desaturations during treatment (p0.001, t=5.74). When using a laryngeal mask, the average
amount (in ml) of propofol used was significantly higher (p0.016, t=-2.22) and the average waking up time in minutes significantly
longer (p0.016, t=-2.23).
It was also found that deepening the sedation to be able to insert the laryngeal mask
effectively reached such a level that it should be renamed as anaesthesia, thereby possibly limiting its use to hospital settings. The
study supported, however, the safety aspects of the laryngeal mask.
Vol.3 – n.1/2002
Harvard: J. S. Veerkamp, T. Porcelijn, R. J. Gruythuysen (2002) "Dental treatment of children using propofol and a laryngeal mask", European Journal of Paediatric Dentistry, 3(1), pp14-21. doi:
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