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Home Asthma inhalers and subsurface enamel demineralisation: an in situ pilot study

Asthma inhalers and subsurface enamel demineralisation: an in situ pilot study

Authors:

  • R. Tootla
    Dept. Paediatric Dentistry, Leeds Dental Institute, Leeds, England
  • G. Kotru
    Dept. Paediatric Dentistry, Leeds Dental Institute, Leeds, England
  • M. A. Connolly
    Dept. Paediatric Dentistry, Leeds Dental Institute, Leeds, England
  • M. S. Duggal
    Dept. Paediatric Dentistry, Leeds Dental Institute, Leeds, England
  • K. J. Toumba
    Dept. Paediatric Dentistry, Leeds Dental Institute, Leeds, England

ABSTRACT


Aim

The purpose of this pilot study was to identify the subsurface enamel demineralising potential of two possible acidogenic
lactose-based powders and their corresponding generic pump inhalers.

Methods

Ten healthy non-asthmatic adults participated in a 5-leg randomised crossover study including a 10 sucrose control. A twice-daily 400 g dose of inhaler was applied in vitro to a demineralised enamel slab on the buccal flange of a mandibular removable appliance before in situ placement for 14 days each.
Lesion parameters were determined using transverse microradiography and digitised image analysis.

Results

Minimal demineralisation occurred with sucrose, both pump and one powder inhaler. The remaining powder was associated with remineralisation (p = 0.29). Overall, mean lesion depth increased (p = 0.12).

Conclusion

Asthma inhalers failed to demonstrate a significant acidogenic/cariogenic effect.

PLUMX METRICS

Publication date:

Sep /2005

Keywords:

asthma inhalers, dental caries, enamel demineralisation

Issue:

Vol.6 – n.3/2005

Page:

139 – 143

Publisher:

Ariesdue

Cite:


Harvard: R. Tootla, G. Kotru, M. A. Connolly, M. S. Duggal, K. J. Toumba (2005) "Asthma inhalers and subsurface enamel demineralisation: an in situ pilot study", European Journal of Paediatric Dentistry, 6(3), pp139-143. doi:
Vancouver: R. Tootla, G. Kotru, M. A. Connolly, M. S. Duggal, K. J. Toumba. Asthma inhalers and subsurface enamel demineralisation: an in situ pilot study. European Journal of Paediatric Dentistry [Internet]. 2005Sep.1 [cited 2023Mar.25];6(3):139-143. Available from: https://www.ejpd.eu/abstract-pubmed/asthma-inhalers-and-subsurface-enamel-demineralisation-an-in-situ-pilot-study/
MLA: R. Tootla, G. Kotru, M. A. Connolly, M. S. Duggal, K. J. Toumba Asthma inhalers and subsurface enamel demineralisation: an in situ pilot study. European Journal of Paediatric Dentistry. 2005;6(3):139-143

Copyright (c) 2021 Ariesdue

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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    European Journal of Paediatric Dentistry © | ISSN (Online): 2035-648X
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