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Evaluation of antibiotic mix in Non-instrumentation Endodontic Treatment of necrotic primary molars

Type:  Articles

Pubblication date:  19/2017

Authors:  N. Raslan*, O. Mansour**, L. Assfoura*

Language:  English

Institution:  Tishreen University, , Latakia, Syria *Faculty of Dentistry, Department of Pediatric Dentistry **Faculty of Pharmacy, Department of Medicinal Chemistry and Drugs Quality Control

Publication:  European Journal of Paediatic Dentistry

Publisher:  Ariesdue Srl

Keywords:  Antibiotic mix; Necrotic primary molars, Non-instrumentation endodontic treatment; Root resorption.

Email:  [email protected]

Title:  Evaluation of antibiotic mix in Non-instrumentation Endodontic Treatment of necrotic primary molars

Abstract:  Aim To compare the clinical and radiographic success rates of an antibiotic mix consisting of metronidazole, minocycline and ciprofloxacin (3Mix-MP) and another mix where minocycline was replaced with clindamycin (3Mix-MP-R) in non-instrumentation endodontic treatment (NIET) of necrotic primary molars and to determine the effect of root resorption on the success of the treatment. Materials and methods Forty-two necrotic mandibular primary molars from 22 healthy children were randomly assigned to either mixture. Blinded clinical evaluation was conducted after 1, 3, 6 and 12 months by the operator, and blinded radiographic evaluation was conducted at 6 and 12 months follow-ups by other two investigators with inter-examiner reproducibility of 0.95. Results Overall success rates of 3Mix-MP and 3Mix-MP-R were 80.96% and 76.20% respectively, with no statistically significant difference. Radiographically, resorption of more than one third of the root length had a lower failure rate with no statistically significant difference (p<0.5). Conclusion Primary teeth with necrotic pulp can be treated with 3Mix-MP or 3Mix-MP-R irrespective of the degree of root resorption.

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European Journal of Paediatric Dentistry | ISSN (Online): 2035-648X |
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